Resectable stage IVA/IVB tumors should be treated with surgery followed by chemoradiation, with consideration for dabrafenib/trametinib biotherapy for BRAFV600E-mutated tumors.
![](https://www.enttoday.org/wp-content/uploads/2016/09/ENT_0916_pg6a.png)
Resectable stage IVA/IVB tumors should be treated with surgery followed by chemoradiation, with consideration for dabrafenib/trametinib biotherapy for BRAFV600E-mutated tumors.