Over the past few decades, a transition toward culture-directed antibiotics has shifted the treatment paradigm of SBO toward primary medical management, with mortality rates now decreasing to 10-20% compared to 50% initially.
Can Calcitonin Levels Guide Prophylactic Neck Dissection in Sporadic Medullary Thyroid Carcinoma?
Medullary thyroid carcinoma (MTC) comprises less than 5% of thyroid cancers but is responsible for more than 10% of deaths related to thyroid cancer.
Can Anticoagulation Be Safely Continued in Most Otolaryngologic/Head and Neck Surgery?
Antithrombotic management is a key component of surgical optimization, as it necessitates balancing the risk of a peri-operative thrombotic event with the risk of bleeding.
Is p16 Testing Sufficient as a Surrogate for HPV-Related Squamous Cell Carcinoma?
The use of p16 as a surrogate marker for HPV has gained traction, but is it sufficient as a surrogate for HPV-related squamous cell carcinoma?
Are Cephalosporins Safe for Surgical Prophylaxis in Patients with Penicillin Allergy?
Most current literature suggests that cefazolin is safe for surgical prophylaxis in patients with penicillin allergy.
Why Wait Until After Surgery? The Case for Pre-habilitation in Head and Neck Cancer Care
Multimodal pre-habilitation and rehabilitation have been an important topics in the literature, aiming to combat modifiable patient factors like sarcopenia, malnutrition, and psychological status.
Anaplastic Thyroid Cancer Treatment by Multidisciplinary Palliative, Radiation, Oncology, and Surgical Teams
Resectable stage IVA/IVB tumors should be treated with surgery followed by chemoradiation, with consideration for dabrafenib/trametinib biotherapy for BRAFV600E-mutated tumors.
Nuclear Medical Imaging Is Recommended in the Diagnosis and Management of Head and Neck Paragangliomas
Nuclear medical imaging is strongly recommended in the diagnosis of paragangliomas that are familial, SDHB variants, malignant, or potentially multifocal, but those that have classic presentations do not routinely require peptide receptor imaging.
What Is the Role of Induction Chemotherapy in the Treatment of Locally Advanced Sinonasal Squamous Cell Carcinoma?
Sinonasal neoplasms have a wide spectrum of histopathologies and biological behaviors, but close proximity to critical structures, such as the skull base and orbit, can make surgical resection a challenge.
What Is the Role of Adjuvant Radiotherapy in Head and Neck Melanoma in the Era of Systemic Therapy?
In the era of effective adjuvant systemic therapies, the use of ICI alone in the adjuvant setting may be insufficient to effectively reduce regional failure.
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