Dupilumab is a novel monoclonal antibody that shows promise in treating patients with CRSwNP who fail initial medical management. ESS, the mainstay therapy for CRSwNP, has been shown to be clinically effective and cost-effective when compared to long-term medical management.
Diclofenac Sodium Not Inferior to Hydrocodone/Acetaminophen for Postoperative Pain After Endoscopic Sinus Surgery
This study provides additional evidence that we may be able to minimize narcotic pain medication use and reserve it for patients who are uncontrolled on NSAIDs alone.
Prolonged Operative Time Associated with Multiple Adverse Outcomes in Endoscopic Sinonasal Surgery
Prolonged operative time is associated with several adverse outcomes following endoscopic sinonasal surgery, including prolonged hospital length of stay, overall surgical complications, and bleeding.
Nasal Discharge the Sole Symptom Improved by Nasal Saline Treatment in Patients with Acute Rhinosinusitis
Nasal discharge was the only symptom significantly improved by nasal saline treatment in patients with acute rhinosinusitis.
No Benefit to Using Povidone-Iodine over Saline as a Nasal Irrigation After Sinonasal Surgery
A dilute 0.1% PVP-I nasal irrigation as a postoperative care modality after rhinomanomesinonasal surgery does not provide additional benefit compared with normal saline irrigation.
Spreader Graft Placement Found Comparable in Functional Outcome in Patients with Nasal Obstruction
Septorhinoplasty with spreader graft placement with and without upper lateral cartilage release provides clinically and statistically significant improvement.
Upper Lateral Cartilage Mucosal Flap Enables the Successful Closure of Larger Septal Perforations
The ventral surface of the upper lateral cartilage can provide additional mucosa for incorporation into a superior advancement flap to achieve successful closure for larger septal perforations.
Molecular View Sheds Light on the Mechanics of Olfactory Receptors
A look at how individual olfactory receptors flexibly recognize diverse odorants in terms of structure and mechanics.
No Inherent Increased COVID-19 Infection Risk in Patients with Chronic Rhinosinusitis
Patients with CRS are likely not inherently more vulnerable to COVID-19 infection at a rate above that of the general population.
Hippocampal Volume Shown on MRI Correlates with Olfactory Performance in Patients with Cognitive Impairment
A look at what neurodegenerative changes can be observed with MRI in patients with olfactory impairment and mild cognitive impairment (MCI) or dementia.
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