Caution should be used when considering biologics such as dupilumab as a first-line therapy for recalcitrant CRSwNP when viable revision surgical alternatives exist.
Endoscopic Nasopharyngectomy Shown Comparably Effective to Intensity-Modulated Radiotherapy in Treating Patients with Recurrent Nasopharyngeal Carcinoma
Salvage Endoscopic Nasopharyngectomy exhibits comparable efficacy but less toxicity than IMRT in carefully screened patients with locally advanced rNPC.
No Association Found Between Frailty and Outcome or Complications in Patients Receiving Endoscopic Cerebrospinal Fluid Leak Repair
Study suggests that the endoscopic approach to cerebrospinal fluid (CSF) leak repair is well tolerated in the frail population.
Extended Modulator Therapy Does Not Improve Olfactory Dysfunction in Patients with Cystic Fibrosis-Related Chronic Rhinosinusitis
Olfactory dysfunction (OD) in adults with CF did not improve in a clinically relevant manner after two years of ETI.
Temperature-Controlled Radiofrequency Neurolysis of the Posterior Nasal Nerve Effective Long Term in Patients with Chronic Rhinitis
What is the long-term safety and effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve in patients with chronic rhinitis?
Placebo-Controlled Study Shown Viable in Evaluating Efficacy of Balloon Eustachian Tuboplasty
The multicenter, double-blind, randomized, placebo-controlled trial protocol was shown to be feasible and demonstrated the need for blinded randomized controlled trials to objectively measure the efficacy of balloon Eustachian tuboplasty.
Pre-Existing Anxiety/Depression May Aggravate Dysphagia in Patients with Normal Swallowing Function
Although anxiety/depression may aggravate dysphagia in patients with normal swallowing function, this correlation may not hold in those with objective swallowing dysfunction.
Telehealth Survivorship Programs for Head and Neck Cancer Patients Shown Feasible and Cost-Effective
Although telehealth survivorship programs are feasible and cost-effective and associated with improved patient outcomes, they might not be ideal for every patient.
Objective Patterns of Olfactory Impairment and Reduced Olfactory Threshold Shown in Patients with Uncontrolled Chronic Rhinosinusitis
Patients with uncontrolled chronic rhinosinusitis (CRS) demonstrate distinct patterns of olfactory impairment, and a reduced olfactory threshold is highly associated with uncontrolled CRS.
> 80% Drop in Post-Excision Intraoperative Parathyroid Hormone Predicts High Rate of Cure in Both Classical and Normohormonal Primary Hyperparathyroidism
Patients with normohormonal primary hyperparathyroidism undergoing parathyroidectomy can expect cure rates like those of patients with classical primary hyperparathyroidism, with an 80% drop or more in intraoperative parathyroid hormone levels predicting a high likelihood of cure.
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