Can a simple scoring system identify individuals at high risk of esophageal cancer?1 Background: The prevalence of esophageal cancer is rapidly expanding. The prognosis for late stage esophageal cancer is dismal, […]
Voice Prosthesis Seals Small Pharyngocutaneous Fistulas After Total Laryngectomy
What management is possible for small pharyngocutaneous fistulas (PCFs) in patients with limited survival chance who are not candidates for surgery? Background: Some of the most common complications following total laryngectomy […]
Chemotherapy Alone Not Recommended for Advanced Laryngeal or Hypopharyngeal Cancer
Is treatment with chemotherapy alone feasible for advanced laryngeal or hypopharyngeal squamous cell carcinoma? Background: A favorable response to induction chemotherapy has been shown to be predictive of response to chemoradiation […]
Survival Rates Comparable in Children and Adults with Oral Tongue Squamous Cell Cancer
Does young age adversely affect prognosis for oral squamous cell carcinoma? Background: Squamous cell carcinoma in young patients (<40 years of age) is believed to have an etiology that is distinct […]
The Application of Posterior Hyoid Space to the Sistrunk Procedure
If the recurrence of thyroglossal duct cysts (TGDC) occurs as a consequence of incomplete resection, will the application of the posterior hyoid space (PHS) to the Sistrunk procedure minimize the […]
A Contemporary Review of Papillomavirus and Oropharynx Cancer
What is the evidence for the role of human papillomavirus (HPV) in the etiology of oropharyngeal cancers, methods of viral detection and the resulting clinical implications? Background: The incidence of head […]
Bioabsorbable Miniplates for Subglottic Stenosis Are Safe and Effective
What is the efficacy and safety of bioabsorbable miniplates as an alternative to autologous grafts in single-stage laryngotracheal reconstruction for subglottic stenosis? Background: Since the 1960s, the incidence of acquired subglottic […]
Laryngeal Framework Surgery Has High Level of Efficacy
What are the success and complication rates of laryngeal framework surgery (LFS), including medialization laryngoplasty (ML) and arytenoid adduction (AA)? Background: Since its introduction in the 1970s, LFS, comprised of ML […]
HPV Status an Independent Prognostic Factor for Oropharyngeal Cancer Survival
What is the independent effect of human papillomavirus (HPV) on oropharyngeal cancer survival? Background: HPV has been associated with oropharyngeal cancer risk and appears to underlie the rising incidence of this […]
Thyroid Palpation Should Follow Serum Hormone Measurement
What are the effects of routine thyroid gland palpation on serum thyroid hormone levels? Background: The assessment of serum thyroid hormone levels in association with thyroid palpation is widely used for […]