Limitations included a small PNI (+) subgroup sample size and the fact that pathologic parameters are not available to aid in preoperative or intraoperative decision making.
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October 2018Citation: Yang X, Tian X, Wu K, et al. Prognostic impact of perineural invasion in early stage oral tongue squamous cell carcinoma: results from a prospective randomized trial. Surg Oncol. 2018;27:123–128.